The LNM Institute of Information Technology

Ashok Garai

ashok.garai@lnmiit.ac.in

Date of joining:

Department:

Physics

Summary

Statistical Mechanics and its application to biological systems, Theoretical and Computational Biophysics, molecular motors, genetic motifs, single molecule biophysics, DNA Nano-mechanics.

Biography

Statistical Mechanics and its application to biological systems, Theoretical and Computational Biophysics, molecular motors, genetic motifs, single molecule biophysics, DNA Nano-mechanics.

Research Area

I am a theoretical and computational biophysicist deeply committed to interdisciplinary research. My expertise and research interests primarily revolve around theoretical and computational biophysics. Throughout my career, I have delved into diverse areas such as molecular motor transport and traffic, the creation of stochastic models for genetic networks, theoretical frameworks for single-molecule biophysics, and the mechanics of DNA nanotechnology. My approach involves crafting quantitative theoretical models to decipher the workings of active biological processes, which I then validate through simulations. Looking ahead, I aspire to explore broader challenges in statistical physics, with a particular emphasis on their applications within the realm of biology.

Personal information

Name

Designation

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ORCID

Scopus_link

Website

Dr. Ashok Garai

Associate Professor

Physics

0000000345589528

24279461100

http://ashokgarai.wixsite.com/scientist-site

Education

	Degree/Diploma	Institute/ Organization	Year	Branch/Specialization
1	Post Doctoral Research	Indian Institute of Science, Bangalore, India	2016	DNA nanomechanics and all atomistic molecular dynamics simulaion
2	Post Doctoral Research	University of California at San Diego, USA	2013	Theoretical modeling to single molecule pulling experiments
3	Post Doctoral Research	Jacobs University of Bremen, Germany	2011	Genetic Network
4	Ph. D. Doctor of Philosophy	Indian Institute of Technology Kanpur	2010	Physics (Molecular Motor Transport and Traffic)

Projects

	Name of Project	Total Cost of Project	Funding Agency	Duration From	Duration To
1	Description: The project involves the study of nanomechanics of DNA and DNA-protein interactions through the concept of various theoretical models of polymer physics and molecular simulations.	2665000	SERB, DST, Government of India	2018	2021

Publications

1	A. Aggarwal, S. Naskar, A. K. Sahoo, S. Mogurampelly, A. Garai and P. K. Maiti, What do we know about DNA mechanics so far?", Current Opinion in Structural Biology, Current Opinion in Structural Biology (Elsevier), 64, 42 JULY 2020 ,
2	A. Garai, D. Ghoshdastidar, S. Senapati, and P. K. Maiti, Ionic liquids make DNA rigid", J. Chem. Physics (AIP, USA), 149, 045104 JULY 2018 ,
3	Ashok Garai, Santosh Mogurampelly, Saientan Bag, Prabal K. Maiti, , Overstretching of B-DNA with various pulling protocols: Appearance of structural polymorphism and S-DNA, Journal of Chemical Physics (AIP, USA), 147, 225102. DEC 2017 ,
4	A. Garai, S. Saurabh, Y. Lansac, and P. K. Maiti, DNA elasticity from short DNA to nucleosomal DNA, J. Phys. Chem. B (ACS, USA), 119, 11146 2015,
5	A. Garai, Y. Zhang, and O. K. Dudko, “Conformational dynamics through an intermediate”, J. Chem. Phys. (AIP, USA), 140, 135101 2014 ,
6	A. Garai, J. Mani, and D. Chowdhury, "Footprint traversal by adenosine-triphosphate-dependent chromatin remodeler motor",, Physical Review E (APS, USA), vol. 85, 041902 2013 ,
7	7 A. Garai, B. Waclaw, H. Nagel, and H. Meyer- Ortmanns,, Stochastic description of a bistable frustrated uni, J. Stat. Mech.: Theory and Experiment, P01009 2012 ,
8	A. Garai, and D. Chowdhury, Stochastic kinetics of a single-headed motor protein: Dwell time distribution of KIF1A, Europhysics Letters, 93, 58004 2011 ,

Workshop attended

	Type	Month	Year	Information
1	Conference - National	November	2020	Invited talk at the "International Conference on Macromolecules- 100 Years of Polymer Science- From Past to Future (ICM-2020)" November 13-15 2020, Kerala, India.
2	Training	May	2019	Invited talk at "The 2nd International Conference on Material Strength and Applied Mechanics (MSAM 2019)" May 27-30 2019, Kiev, Ukraine
3	Training	April	2019	Invited talk at the “3rd North-West Meeting on Spectroscopy, Structure and Dynamics (SSD-2019)”, IIT Roorkee, Roorkee.
4	Conference - National	October	2019	Invited talk at "Rajasthan Science Congress - 2019", October 14-16 2019, MLSU, Udaipur, Rajasthan
5	Training	January	2018	Invited talk in the ISCBC-2018, Manipal University, Jaipur.
6	Training	March	2018	Invited speaker in North West Meeting on Spectroscopy, Structure, and Dynamics -2018, MNIT, Jaipur
7	Training	March	2018	Invited speaker in National Conference on Recent Trends and Advances in Material ans Physical Sciences - 2018; LMCST, Jodhpur.
8	Training	May	2018	Invited talk at the Soft Matter Young Investigator's meeting, Koti Resort, Shimla, India.
9	Training	March	2017	Invited talk in the Conference on DNA Physics, BITS Pilani
10	Training	October	2017	Speaker in the ICTS discussion meeting: "Collective Dynamics of-, on- and around Filaments in Living Cells: Motors, MAPs, TIPs and Tracks", ICTS, Bangalore.